A Case of Blistering Eruptions in Systemic Lupus Erythematosus
Published: September 1, 2019 | DOI: https://doi.org/10.7860/JCDR/2019/42338.13155
Sarojini Raman, Abhimanyu Grover, Prasant Padhan, Urmila Senapati
1. Associate Professor, Department of Pathology, KIMS, BBSR, Bhubaneswar, Odisha, India.
2. Postgraduate Resident, Department of Pathology, KIMS, BBSR, Bhubaneswar, Odisha, India.
3. Associate Professor, Department of Pathology, KIMS, PBMH, Bhubaneswar, Odisha, India.
4. Professor and Head, Department of Pathology, KIMS, BBSR, Bhubaneswar, Odisha, India.
Correspondence
Dr. Sarojini Raman,
Department of Pathology, KIMS, Campus-5, Kiit Campus, BBSR, Bhubaneswar-751024, Odisha, India.
E-mail: sraman10371@gmail.com
Cutaneous vesiculobullous lesions have a wide aetiological spectrum ranging from autoimmunity to medications and infections. Systemic Lupus Erythematosus (SLE) is one of most frequent autoimmune diseases with its cutaneous form being very uncommonly encountered. We report a case of Bullous Systemic Lupus Erythematosus (BSLE). Patient presented with fever, arthalgia and widespread blistering eruptions on face, neck and upper chest wall. Skin biopsy revealed subepidermal bulla and Direct Immunofluorescence (DIF) showed deposition of IgG, IgA, IgM, C3, C1q at the dermoepidermal junction. On treatment lesions healed rapidly. So proper clinical acumina is essential for diagnosis and management of such cases excluding the differentials.
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